brain and central nervous
system and thereby relieve symptoms of depression.
An excellent way to describe the effects of sceletium is through a simple metaphor. Think of your mind as a reasonably well-tuned four-cylinder engine.
About half an hour after consuming between 50 – 100 milligrams of sceletium, your mind is more like a twelve-cylinder, turbo-charged racing engine.
Soon your mind is overcome with startling clarity, a feeling that anything is possible, and a seemingly endless capacity for ideas and mental work. If coffee is a pick-me-up, sceletium is a jet ride to mental brilliance.
The vast effects of sceletium seem primary due to a group of alkaloids, notably mesembrine, mesembrenol, and tortuosamine.
These compounds interact with receptors in the brain, enhancing the production of dopamine, which is our primary inner pleasure chemical, and prolonging the activity of serotonin, a critically important mood compound.
The net effect of sceletium ingestion is a feeling of great well-being, heightened awareness, mental alertness and a keen-mindedness that is quite pronounced.
But there is far more than just a feel-good effect and terrific mental stimulation to sceletium.
The plant appears to be an excellent anti-depressant and anti-anxiety aid. It could potentially be used by people with low spiritual energy, mild-to-moderate depression, and anxiety disorder.
In one study of the effects of sceletium reported in the Journal of Ethnopharmacology, the main alkaloids of the plant demonstrated the capacity to extend the activity of serotonin.
This activity, known as SSRI, or selective serotonin reuptake inhibition, is primarily how pharmaceutical antidepressant drugs work.
The difference with sceletium is that it is a multi-compound plant and does not appear to demonstrate comparable hazardous effects of antidepressants, which can include gastrointestinal disorders, loss of sex drive, insomnia and exacerbated depression.
One significant difference between sceletium and other agents used to manage depression or anxiety is that sceletium is available as an herbal supplement and does not require a prescription.
Most people tolerate sceletium well, although there are some reports of mild headaches among users.
In its long history of use, no significant adverse effects of sceletium have been noted. This makes sceletium a worthy candidate for consideration in cases of depression and anxiety.
Is sceletium a miracle cure? No. Will sceletium erase all cases of depression and anxiety? No. But sceletium will likely enjoy a significant spot in the market as an unusually effective mind and mood enhancer, and a good first option for mild to moderate mood disorders.
Chris Kilham is a medicine hunter who researches natural remedies all over the world, from the Amazon to Siberia.
Chris advises herbal, cosmetic and pharmaceutical companies, is a regular guest on radio and TV programs worldwide, and is the author of fifteen books. Read more at MedicineHunter.com.
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